People donate plasma every day. Your plasma will be collected by trained medical professionals, in a sterile environment. Donating plasma is a safe process. Most healthy adults can donate blood and plasma with no side effects. Some people may have minor side effects like dehydration, fatigue or dizziness. We will screen the Donors to collecting plasma to make sure they are good candidates.


To donate plasma for use in COVID-19 patients, you must have been sick with COVID-19 and completely recovered. You should have been free of symptoms for two weeks.


Plasma is the clear liquid portion of blood that remains after blood cells, platelets, and other cellular components are removed. It contains water, salts, antibodies, and other proteins. It is collected from healthy, voluntary donors through a process called plasmapheresis. Plasma is regularly collected to produce therapies to treat people with many types of disorders, including immunodeficiency, hemophilia and trauma, such as burns or shock.


  • They are 18+ years of age
  • They have laboratory-confirmed diagnosis of infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes COVID-19.
  • They are admitted to an acute care facility for the treatment of COVID-19 complications.
  • They have severe or life-threatening COVID-19, or judged by the treating doctor to be at high risk of progression to severe or life-threatening disease.
  • There is an informed consent provided by the patient or the health care proxy.


  • Shortness of breath (dyspnea)
  • Respiratory frequency ≥ 30/min
  • Blood oxygen saturation ≤ 93%
  • Partial pressure of arterial oxygen to fraction of inspired oxygen ratio < 300
  • Lung infiltrates > 50% within 24 to 48 hours


  • Respiratory failure
  • Septic shock
  • Multiple organ dysfunction or failure


  • Plasma donors should be at least 18 years old, but less than 65 years old.
  • Plasma donors should have tested positive for COVID 19
  • Plasma donors should have recovered from symptoms of COVID like fever, cough, cold, breathing difficulties at least 14 days prior to donating their plasma.
  • Plasma donors should test non-reactive for transmissible viruses including HIV and Hepatitis
  • Plasma donors should test negative for endemic infectious diseases like Tuberculosis or Malaria
  • Plasma donors should not have ever been pregnant.
  • Individuals must have had a prior diagnosis of COVID-19 documented by a laboratory test and meet other donor criteria.
  • A negative lab test for active COVID-19 disease is not necessary to qualify for donation.


You must have a pre-donation medical examination which includes answering medical history questions, tests for viruses such as HIV and Hepatitis and evaluating your hemoglobin levels.


Most people compare the feeling of the needle to a mild bee sting or pinprick.


The process usually takes around 30- 45 minutes.


You can donate 500ml (1 pint) of blood


Each patient requires 200 ml of plasma.


It’s advised to refrain from alcohol consumption 24-48 hours before plasma donation.


A baby contains genetic material from both the mother and the father. So, when a woman gets pregnant, she develops antibodies against the father’s genetic material [human leukocyte antigen]. This HLA antibody can lead to a transfusion related complication called Transfusion related acute lung injury (TRALI). Covid-19 patients already have compromised lungs, plasma with HLA antibody might increase their chances of lung damage.